Santana Lopez
General Information
Gender: Female
Age: 18
Hair Color: Dark Brown
Eye Color: Dark Brown
Height: 5'5"
Occupation(s): Former high school student
Family & Friends
Family: Maribel Lopez-mother
Dr. Lopez-father
Alma Lopez-grandmother
Relationships: Brittany Pierce-in love with, on hold
Noah Puckerman-ex-boyfriend
Sam Evans-ex-boyfriend
David Karofsky-beard
Finn Hudson-friends, sexual-ended
Sexuality: Lesbian
Enemies: Vocal Adrenaline, Josh Coleman, Kitty
Other Information
Education: William McKinley High School-former
Series Information
First appearance: Pilot
Portrayer: Naya Rivera

Santana Lopezis a main character in Glee. She is an alumna of William McKinley High School, where she served as the co-captain of the Cheerios, and a member of the school's glee club, New Directions. She was previously a member of the all-girls second glee club, The Troubletones. As of Season Four she is a student at The University Of Louisville where she has been given a scholarship in Cheerleading. Although Santana has a history of relationships with male characters, she is a lesbian and as of Pot O' Gold (Season 3) currently in a relationship with her best friend Brittany Pierce, with whom she had previously maintained a 'friends-with-benefits' arrangement. In Season 3, Santana deals with her coming out as a lesbian and being in a relationship with Brittany. Santana is portrayed by Naya Rivera.

Santana is introduced as an antagonist alongside Quinn and Brittany (The Unholy Trinity) as one of the three most popular cheerleaders at school. She is seen as a bitchy cheerleader who remarks on her cruel attitude. It is later revealed that the motivations behind Santana's antagonism and her sexual aggressiveness towards boys is due to the fact that she is struggling with her romantic feelings towards Brittany, and subsequently with her lesbian identity. However, in Season 3 she finally comes out and is proud of her sexuality and herself.